Overview of Oxidized Regenerated Cellulose (ORC)

This is an overview of Oxidized Regenerated Cellulose (ORC), a biocompatible material with excellent hemostatic properties that is widely used in surgical procedures to control bleeding.

ORC Composition and Properties

ORC is derived from cellulose, a natural polymer found in plants, and is chemically modified by oxidation to create a material with a high degree of carboxyl and aldehyde groups. These functional groups give ORC its unique properties, including its hemostatic activity and biocompatibility.

We describe the key characteristics of ORC, noting that it is a white-yellowish, fibrous material that can be formed into a variety of shapes and sizes. It is highly absorbent and can hold up to 20 times its weight in fluid, and it has a high surface area that allows it to interact with blood and other fluids to promote clotting and wound healing.

Types of ORC Products

There are four different types of ORC products: Standard, Knit, Pillow, and Fibril. Each of these products has distinct properties and is suited for different surgical applications. The Standard ORC is a loose-knit that provides a matrix for platelet adhesion and has a proven bactericidal effect. The Knit ORC has a dense weave structure that is designed for severe bleeding and can be easily sutured. The Pillow ORC is a structured non-woven fabric with interlocking fibers that provide extra hemostasis. The Fibril ORC is a soft, lightweight material that can be applied in layers and is ideal for mild bleeding sites.

Versatility and Future Applications

We would like to highlight the versatility of ORC and its wide range of applications in healthcare. As research in this field continues, we can expect to see even more innovative uses for ORC in the future. 

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